Check out this post - seems to be a brand-spanking new management API in the Microsoft.Web.Administration namespace:

Here's a quick graphical overview from that blog post:

 

And here's a "The Gu" post on

Something like this will find all the sites, their application and their virtual directories in your IIS7 server:

static void Main(string[] args)    {        ServerManager mgr = new ServerManager();        foreach(Site s in mgr.Sites)        {            Console.WriteLine("Site {0}", s.Name);            foreach(Application app in s.Applications)            {                Console.WriteLine("\tApplication: {0}", app.Path);                foreach(VirtualDirectory virtDir in app.VirtualDirectories)                {                    Console.WriteLine("\t\tVirtual Dir: {0}", virtDir.Path);                }            }        }        Console.ReadLine();    }